Abstract

Diffuse uterine leiomyomatosis (DUL) is a rare condition that poses a unique management challenge in women who desire fertility. The need to resect innumerable uterine myomata must be balanced with the desire to retain fertility potential in these women. Hysteroscopic myomectomy is the treatment of choice for DUL as myomas with submucosal or intracavitary components are the main cause of menorrhagia and impaired fertility, and hence resection of these myoma with the aim of achieving a normal-looking endometrial cavity would optimize reproductive outcome. We report the case of a woman with DUL who was managed with hysteroscopic myomectomy in which 17 submucosal myomas were removed followed by a successful pregnancy.